Patients in the study may take other drugs besides Cetirizine hydrochloride and Omeprazole. In a recent study, comparing IR-OME 40 mg suspension, lansoprazole 30 mg, esomeprazole 40 mg given at 10:00 pm on an empty stomach (last meal at 5:00 pm) for 7 days found that IR-OME was superior to the others in speed of overnight pH control and sustained pH control in the first 4 hours of the sleeping period compared to both lansoprazole and esomeprazole (Table 16-1). Omeprazole is a proton pump inhibitor (PPI). Page last reviewed: 18 November 2021 The risk is greater in women, people younger than 30, and with higher dosages. Adults20 or 40 milligrams (mg) one, two, or three times a day before a meal. Do not chew or crush the pellets. All information is observation-only. Most people heal within 4 weeks. Suzuki T, Yamaguchi T, Odaka T, Kobayashi M, Seza A, Kouzu T, Yokosuka O. Aliment Pharmacol Ther. Click here for an email preview. Omeprazole takes around 1 hour to block the production of stomach acid, and its maximal effect occurs around 2 hours after taking the pill. For a full list, see the leaflet inside your medicine packet. Aug 13, 2019 #2 MargaretM and Tomlin like this. Shake the syringe right away and leave it for 2 to 3 minutes to thicken. Administer on an empty stomach at least one hour before a meal. M any people know that taking a sedative and an antihistamine at the same time can cause extreme drowsiness, or that taking an anti-inflammatory like Advil , Aleve or Motrin while you're on a blood thinner raises the risk of hemorrhaging. People can also use over-the-counter (OTC) omeprazole to relieve heartburn or acid reflux. This can potentially lead to more side effects, such as drowsiness and involuntary eye movements. If you miss a dose of this medicine, take it as soon as possible. Also see your doctor if you develop any muscle cramps, spasms, or weakness; jitteriness; abnormal heartbeat; dizziness; seizures; or any other symptoms of concern. Aliment Pharmacol Ther. Taking antibioticsespecially those in the tetracycline familyalong with iron supplements can dampen the effects of the antibiotics, making them less likely to work, Dr. Glatter says. If your or your child's condition does not improve, or if it becomes worse, check with your doctor. Last updated on Aug 17, 2022. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). 8600 Rockville Pike Can be used for the short-term treatment of active duodenal ulcer in adults. It works by decreasing the amount of acid your. Iron and green tea. Animals Sitemap . Anti-diarrhoeal - to administer at the first signs of diarrhoea. Antidepressants and St Johns wort both increase levels of the feel-good brain chemical serotonin. Prilosec, Protonix or . All 5 available agents are extremely effective and safe and are each reasonable choices for initial therapy. This can cause serotonin syndrome and in severe cases, it may lead to muscle rigidity and seizures, he says. The proton pump is located in the parietal cells of the stomach wall. Oral metoclopramide can be given with or without food, but it typically works best when given about 20 minutes before a meal. The dose is usually 2.5 to 10 mg once a day before a meal. A slow increase of dose may improve gastrointestinal tolerability. The dose is usually 5 to 20 mg once a day before a meal. If you are one of the 95 million Americans with high cholesterol, you might like the idea of taking a natural supplement to lower your levels. More specifically, they are proton pump inhibitors which prevent the formulation of hydrochloric acid. Different individuals may respond to medication in different ways. privacy practices. Additionally, we often add in an acid blocker such as an H2 blocker (i.e. An evening dose of a delayed-release PPI should control intragastric pH into the critical part of the sleeping period and be sufficient for most patients. Although not all of these side effects may occur, if they do occur they may need medical attention. Do not chew or crush the pellets. It's best to take ibuprofen with, or just after, a meal so it does not upset your stomach. If your dose is different, do not change it unless your doctor tells you to do so. Dosage of drugs is not considered in the study. It is unknown how omeprazole affects a breastfeeding infant. Omeprazole decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed areas of gastrointestinal tissue. For patients receiving continuous feeding through a tube, feeding should be temporarily stopped about 3 hours before and 1 hour after administration of omeprazole powder for oral suspension. It may also interact with drugs metabolized through the cytochrome P450 pathway (particularly CYP2C19 and CYP3A4). Ask your healthcare professional how you should dispose of any medicine you do not use. Do not keep outdated medicine or medicine no longer needed. Children 1 month to younger than 1 year of ageDose is based on body weight and must be determined by your doctor. The usual starting dose is one tablet of 500 mg or 850 mg once daily, given during meals or after meals. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Empty packet of powder into a small cup containing 2 tablespoons of water. Check with your doctor right away if you have black, tarry stools, blistering, peeling, or loosening of the skin, chest pain, chills, cough, diarrhea, itching, joint or muscle pain, painful or difficult urination, red irritated eyes, red skin lesions, often with a purple center, sore throat, sores, ulcers, or white spots in the mouth or on the lips, swollen glands, unusual bleeding or bruising, or unusual tiredness or weakness. We study millions of patients and 5,000 more each day. Although most people tolerate omeprazole well, there are certain risks when people use it for a long period of time. Omeprazole is best used short-term. Please enable it to take advantage of the complete set of features! Dont miss these signs your body is running low on key vitamins. Check with your doctor right away if you or your child has a change in frequency of urination or amount of urine, blood in the urine, fever, joint pain, loss of appetite, skin rash, swelling of the body, feet, or ankles, unusual tiredness or weakness, or unusual weight gain after receiving this medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. One of the important duloxetine interactions to keep note of is that between Cymbalta and Abilify. Medically reviewed by Carmen Fookes, BPharm. This is a big one to be aware of. These are some other foods you shouldnt eat with certain medications. Ask your doctor if you have any questions. Insights into the future of gastric acid suppression. Pets with multiple and/or serious health problems often end up taking many medications, and the more they take, the greater the risk that an adverse reaction might occur. Can a massage technique help treat acid reflux? Swallow the capsule and tablet forms of omeprazole whole. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you are taking this medicine to treat an ulcer that is associated with an H. pylori infection, take it together with antibiotics (eg, amoxicillin, clarithromycin) at the same time of day. Children younger than 1 month of ageUse and dose must be determined by your doctor. On day 8, daytime intragastric pH > 4 following treatment with omeprazole (median: 55%) or a combination of omeprazole and famotidine (61%) was superior (p < 0.05) to that with famotidine (21%). This mixture must be swallowed immediately with a glass of cool water. ChildrenUse and dose must be determined by your doctor. Hatlebakk JG, Katz PO, Kuo B, Castell DO. Omeprazole. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Researchers have found limited evidence to suggest that omeprazole is present in breast milk. The Food and Drug Administration (FDA) have approved omeprazole capsules and granules for the following medical conditions: People can use OTC omeprazole tablets to treat frequent heartburn that occurs two or more times per week. Learn more in this, Acid reflux is very common and occurs when stomach acid flows back up into the food pipe, where it causes heartburn. Yes the combination should be just fineYes I use the laser on my patients and personal pets regularly with phenomenal success. If you take a multivitamin dont worry, but if you are K deficient and need extra K, take it two hours apart from the other fat-soluble vitamins, he says. If you cannot swallow the omeprazole delayed-release capsules, you may open it and sprinkle the pellets contained in the capsule on one tablespoon of applesauce. A pharmacist can also make one. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. It is safe to take painkillers such as paracetamol or ibuprofen at the same time as omeprazole. A small adjustment in timing, or simply eating breakfast, may improve outcome. It can also be prescribed to prevent and treat vomiting in dogs that may happen with pets prone to motion sickness. The rapid acid control with an H2-receptor antagonist may be combined with the long-lasting antisecretory effect of a proton-pump inhibitor. Speak to your doctor about how drug interactions should be managed. Personalize this study to your gender and age, Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue), Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Cetirizine hydrochloride and Methotrexate, Prochlorperazine Maleate and Small Intestinal Perforation, Implanon and Sudden Unexplained Death In Epilepsy, Amphotericin B and Betamethasone Valerate drug interaction, Cetirizine Hydrochloride and Granulocyte Count Increased, Temazepam and Unexpected Therapeutic Effect. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). World J Gastrointest Pharmacol Ther. To use the delayed-release oral suspension: If you are using the delayed-release oral suspension with a nasogastric or gastric tube: The dose of this medicine will be different for different patients. information submitted for this request. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Omeprazole - Uses, Side Effects, and More Uses Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It may take several days before this medicine begins to relieve stomach pain. Diarrhea, a headache, drowsiness, abdominal pain, nausea or vomiting, or tongue discoloration. In patients with nighttime symptoms, an evening dose before dinner may be effective. If any medicine remains after drinking, add more water, stir, and drink immediately. When these minerals are taken at the same time, they may not be quite as effective, says Tod Cooperman, MD, president of consumerlab.com, an independent testing company focused on health and nutrition products in White Plains, New York. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. The following information includes only the average doses of this medicine. Empty the contents of a 10 mg packet of powder into a container containing 15 mL of water. Again, these necessary minerals will compete for absorption by the body, meaning you get less of each when you take them together, warns Dr. Cooperman. PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole, and others) help reduce the amount of stomach acid made by glands in the lining of . Acid levels return to previous levels within 3 to 5 days of discontinuation. Use only if potential benefits justify the risk. information and will only use or disclose that information as set forth in our notice of Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. Is the ketogenic diet right for autoimmune conditions? Histamine2-receptor antagonists: Rapid development of tachyphylaxis with repeat dosing. Some doctors will detect kidney dysfunction in people taking omeprazole. Use the lowest dose for the shortest amount of time appropriate to the condition being treated. Make sure you know thesuper-important questions to ask before you take prescription medications. (2018). Researchers have not conducted studies on the efficacy of omeprazole past 12 months. H2 blockers. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. When used together, it can increase the effects of Abilify in the body by increasing its blood levels. Stir and leave it for 2 to 3 minutes to thicken. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Abe Y, Inamori M, Togawa J, Kikuchi T, Muramatsu K, Chiguchi G, Kawamura H, Kobayashi N, Kirikoshi H, Sakaguchi T, Takamura T, Nakajima A, Ueno N, Sekihara H. J Gastroenterol. May be considered for the short-term treatment of gastroesophageal reflux disease (GERD) (also known as heartburn) and erosive esophagitis (a severe inflammation of the lining of the esophagus - the tube that carries food from the mouth to the stomach). Shah, N., & Srivastava, P. (2019). They're generally not tested for the effect they have on other medicines. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Dogs with the MDR1 genetic mutation can become very ill or die if given certain medications. Adults60 milligrams (mg) once a day before a meal. Taste disturbances have also been reported but these usually resolve on discontinuation of therapy. Next, be sure to check out these vitamin mistakes you might not know youre making. Omeprazole has active ingredients of omeprazole. Detailed Description: Efficacy of intravenous administration of combined acid suppressants in healthy dogs. The cost of omeprazole depends on the strengths. Children younger than 1 year of ageUse and dose must be determined by your doctor. FOIA Immediate-release omeprazole at bedtime may be used in lieu of the evening dose a delayed-release PPI if nocturnal symptoms are not adequately relieved. Four-day continuous gastric pH monitoring following anti-acid secretory drug administration: cross-over test to assess the early effects. The https:// ensures that you are connecting to the All rights reserved. atomoxetine Strattera Capsule Note: capsule contents can cause ocular irritation - Do not open capsules as contents are an ocular irritant benzonatate Tessalon Perles Capsule Note: swallow whole; local anesthesia of the oral mucosa; choking could occur - Capsules are liquid-filled "perles" - Do not alter (break, cut, chew) integrity Both prescription Prilosec and Prilosec OTC contain the same active ingredient, omeprazole, which effectively stops acid production. See your doctor if you develop any unexplained fever, rash (particularly one that gets worse after you have been in the sun), new or worsening joint pain, persistent diarrhea, or generalized aches and pains. Read and follow these instructions carefully. Sustained daytime control may not be sufficient with IR-OME as a single dose at night. Children younger than 1 month of ageUse and dose must be determined by your doctor. Side effects that children may report are similar to those that adults report, except that they tend to complain more about fever and breathing issues, such as pharyngitis and sinus infections. Use of the tablets in cats to treat nausea and vomiting is 'off label' or 'extra label'. Children 1 to 16 years of ageDose is based on body weight and must be determined by your doctor. Material and methods: Using this medicine with any of the following medicines is not recommended. Available for Android and iOS devices. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. You can easily overdo herbs or supplements with sedative properties. Mayo Clinic does not endorse companies or products. Introduction Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of mortality and morbidity worldwide. Available in capsule and powder form, the 40-mg dose given at bedtime has been shown to be superior to pantoprazole 40 mg given at dinner in control of overnight pH. This is more likely to occur if you are taking this medicine for more than 1 year, or if you are taking this medicine together with digoxin (Lanoxin) or certain diuretics or "water pills". The following table lists the dosing instructions for each use of omeprazole. PPIs like omeprazole ( Prilosec ), rabeprazole, lansoprazole, and esomeprazole are used to treat helicobacter pylori infection, acid reflux, and gastroesophageal reflux disease (GERD). Label: Prilosec OTC- omeprazole magnesium tablet, delayed release. Safety and efficacy have not been established in children younger than 1 month of age. This is one of the six things you should know before you begin taking magnesium supplements. Has also been associated with other conditions such as lupus erythematosus and magnesium deficiency. To treat erosive esophagitis caused by acid-mediated GERD: Adults and children 17 years of age and older20 milligrams (mg) once a day before a meal. May also interfere with some laboratory tests. 2014. This site needs JavaScript to work properly. You're always running to the toilet. PPIs such as omeprazole will block the release of acid, thus decreasing the acidity inside the stomach. Koike T, Ohara S, Sehine H, Kawamura M, Abe Y, Inomata Y, Iijima K, Imatani A, Shimosegawa T. Hepatogastroenterology. In combination with blood pressure medications, this can cause dangerously low blood pressure, he says. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Spacing out the two will help. Aspirin and omeprazole should not be used to treat a sudden onset of heart attack or stroke symptoms (chest pain, sudden numbness or weakness, slurred speech). Some studies report that PPIs may increase the risk of bone fractures. Label: Prilosec- omeprazole magnesium capsule, delayed release. stomach pain. Keep from freezing. Each makes claim to subtle differences in speed of onset of symptom control, bioavailability, and drug interactions, though few direct head-to-head comparisons of these subtle differences are published. However, doctors do not recommend omeprazole tablets for immediate heartburn relief because it can take up to 4 days before it has its full effect. In this study, investigators hypothesized that the plasma concentration of metformin and its glucose-lowering action would be affected by omeprazole, probably by altering the expression or function of OCTs in the liver, its primary target organ, as well as in the kidney. My logic is if I give it to him in a pill pocket and make him swallow the pills once, it would be less stressful than doing the same process twice. Vitamin B-12 deficiency long has been recognized as a serious complication of the diabetes drug metformin. National Library of Medicine This is one of the more common food-drug reactions. Nugent, C. C., & Terrell, J. M. (2019). A: Your friend is the victim of a double whammy. Common interactions include depression among females and drug ineffective among males. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine only as directed by your doctor. WSU is the leader in identifying drugs that may be dangerous for dogs with the MDR1 mutation and can identify alternative medications and doses. Swallow the capsule and tablet forms of omeprazole whole. and famotidine 20 mg b.d. Blood, urine, and other laboratory tests may be needed to check for unwanted effects. A slow increase of dose may improve gastrointestinal tolerability. It also may act as a mild pain control medication. Your doctor may adjust your dose as needed. Serious stomach conditions may occur while taking this medicine alone or together with antibiotics. Expert's Assistant chat. Along with its needed effects, a medicine may cause some unwanted effects. Adults40 milligrams (mg) once a day before a meal. However, researchers have not consistently reported this effect. The phase IV clinical study analyzes what interactions people who take Cetirizine hydrochloride and Omeprazole have. Hatlebakk JG, Katz PO, Camacho-Lobato L, Castell DO. This is a decision you and your doctor will make. All rights reserved. Omeprazole is used to treat conditions associated with high levels of stomach acid, such as indigestion, reflux and ulcers. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Some studies have suggested PPIs (such as omeprazole) are associated with a higher risk of stomach cancer and kidney disease. I routinely recommend before meal dosing, regardless of which proton pump inhibitor is chosen as this eliminates any issue of meal timing and is easy for the patient to remember. . All rights reserved. Nat Rev Gastroenterol Hepatol. Aliment Pharmacol Ther. Disclaimer. May make these conditions worse. After the first day: 40 mg once a day for up to 14 days. Always read the labels to find out what you can expect from supplements. Effect of Helicobacter pylori status on intragastric pH during administration of lafutidine or famotidine. All rights reserved. The table below lists these dosage types, plus their strengths in milligrams (mg). If the doctor recommends taking omeprazole twice daily, the person should take it before breakfast and before supper. include protected health information. Omeprazole is also used to treat dyspepsia, a condition that causes sour stomach, belching, heart burn, or indigestion. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Empty the contents of a 2.5 milligrams (mg) packet of powder into a container containing 5 mL of water. Make sure any doctor or dentist who treats you knows that you are using this medicine. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. To treat erosive esophagitis caused by acid-mediated GERD: Adults and children 17 years of age and older20 milligrams (mg) once a day before a meal. Portions of this document last updated: April 01, 2023. Two possible pills that lower cholesterol levelsred yeast rice and niacindont play well together. Glucophage SR tablets can be used in children from 10 years of age and adolescents. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Patients are too often taking PPIs in the morning and not eating breakfast or taking their drug before bed on an empty stomach. Usually, once a day oral powder, tablet or capsule, that can be administered with food. Omega-3 fish oil supplements may tame inflammation and improve your mood, but when you take these supplements with herbs that thin the bloodsuch as ginkgo biloba or garlicthey may prevent clotting and can lead to uncontrolled bleeding, Dr. Cooperman says. This works to lower the amount of sugar in the blood of people with diabetes. Some drugs may interact with omeprazole. People should tell their doctor which medications they are already taking. If you are a Mayo Clinic patient, this could DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. However, people should not use rilpivirine and rilpivirine-containing antiretrovirals at the same time as taking omeprazole. The dose is usually 5 to 20 mg once a day before a meal. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=61f67858-ba2f-449b-8b30-c15cdaf49222, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a1b077e6-b070-43f2-a98e-380cc635419d, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=35a79458-79f6-44d6-b74c-b4f4aaf0dde0, http://www.ncbi.nlm.nih.gov/books/NBK525994/, https://www.goodrx.com/prilosec?dosage=40mg&form=capsule&label_override=omeprazole&quantity=30%20, http://www.ncbi.nlm.nih.gov/books/NBK539786/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221858/. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Both baseline gastric acid secretion and stimulated gastric acid secretion are affected; the degree that they are affected depends upon the dose of omeprazole. Children 1 to 16 years of ageDose is based on body weight and must be determined by your doctor. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of omeprazole in the elderly. official website and that any information you provide is encrypted 2007 Jun;54(76):1280-4. The study uses data from the FDA. The following information includes only the average doses of this medicine. Many drugs are commonly prescribed for off label use in veterinary medicine. The risk of interactions with omeprazole is greater than with other PPIs such as lansoprazole and pantoprazole. Omeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics. Ondansetron is more of a quick acting anti nausea med. If you notice any other effects, check with your healthcare professional. People taking warfarin to prevent blood clots should use omeprazole with caution because the combination can increase their risk of bleeding. Please follow the instructions on the bottle. She has received numerous awards, including the Arthritis Foundation's Northeast Region Prize for Online Journalism; the Excellence in Women's Health Research Journalism Award; the Journalistic Achievement Award from the American Society for Aesthetic Plastic Surgery; National Newsmaker of the Year by the Community Anti-Drug Coalitions of America; the Gold Award for Best Service Journalism from the Magazine Association of the Southeast; a Bronze Award from The American Society of Healthcare Publication Editors (for a cover story she wrote in, We are no longer supporting IE (Internet Explorer), x things you should know before you begin taking magnesium supplements, vitamins are a waste of money and could even be dangerous, more things to know if you are going to take melatonin, nutrients even nutritionists dont get enough of, signs your body is running low on key vitamins, super-important questions to ask before you take prescription medications, foods you shouldnt eat with certain medications, these vitamin mistakes you might not know youre making, Do not Sell or Share My Personal Information. Bookshelf These side effects may go away during treatment as your body adjusts to the medicine. PPIs are also used to treat other gastrointestinal disorders characterized by excessive acid secretion. Prolonged treatment (greater than 24-36 months) may cause vitamin B12 deficiency. Your doctor may adjust your dose as needed. Children younger than 1 year of ageUse and dose must be determined by your doctor. If any medicine remains after drinking, add more water, stir, and drink immediately. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. This medicine may increase your risk of having fractures of the hip, wrist, and spine. To help relieve this pain, antacids may be taken with omeprazole, unless your doctor tells you otherwise. Cerenia (maropitant citrate) Tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs. Symptoms include numbness, tingling or pain in toes, feet or fingers, trouble walking, memory problems and confusion, depression or burning tongue. This is more likely if you are receiving this medicine for more than 1 year. It can cause bleeding episodes after a fall or injury, and theres a high risk of internal bleeding, he says. Advertising revenue supports our not-for-profit mission. The following table lists the recommended dosages in mg for each use of omeprazole in children based on their weight in kilograms (kg).

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